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Animal Welfare and 3Rs

Publications Melania Osto

  1. Kieler, IN, M. Osto, L. Hugentobler, L. Puetz, MTP. Gilbert, T. Hansen, O. Pedersen, CE Reusch, E. Zini, TA Lutz, CR Bjørnvad. Diabetic cats have decreased gut microbial diversity and a lack of butyrate producing bacteria. Sci Rep. 2019 Mar 18;9(1):4822. PMID: 30886210.
  2. Brandão IR, E. Zini, CE Reusch, TA Lutz, M. Osto. Establishment of a protocol for the isolation of feline pancreatic islets. Physiol Behav. 2018 Mar 15;186:79-81. PMID: 29352965.
  3. Zini E, S. Ferro, F. Lunardi, R. Zanetti, RS Heller, LM Coppola, F. Guscetti, M. Osto, TA Lutz, L. Cavicchioli, CE Reusch. Exocrine Pancreas in Cats With Diabetes Mellitus. Vet Pathol. 2016 Jan;53(1):145-52. PMID: 26319779.
  4. Zini E, F. Lunardi, R. Zanetti, RS Heller, LM Coppola, S. Ferro, F. Guscetti, M. Osto, TA Lutz, CE Reusch, L. Cavicchioli. Endocrine Pancreas in Cats With Diabetes Mellitus. Vet Pathol. 2016 Jan;53(1):136-44. PMID: 26113611.
  5. Osto M, TA Lutz. Translational value of animal models of obesity-Focus on dogs and cats. Eur J Pharmacol. 2015 Jul 15;759:240-52. PMID: 25814247.
  6. Osto M., K. Abegg, M. Bueter, CW le Roux, PD Cani, TA Lutz. Roux-en-Y gastric bypass surgery in rats alters gut microbiota profile along the intestine. Physiol Behav. 2013 Jul 2;119:92-6. PMID: 23770330.
  7. Osto, M., E. Zini, CE Reusch, TA Lutz. Diabetes from humans to cats. Gen Comp Endocrinol. 2012 Dec 14;182C:48-53. PMID: 23247272.
  8. Cani, P.D., M. Osto, L. Geurts, A. Everard. Involvement of gut microbiota in the development of low-grade inflammation and type 2 diabetes associated with obesity. Gut Microbes. 2012 Jul;3(4). PMID: 22572877.
  9. Dietiker-Moretti, S.C., Müller, N. Sieber-Ruckstuhl, F. Tschuor, M. Osto, M. Franchini, M. Ackermann, TA Lutz, CE Reusch, E. Zini. Comparison of a continuous glucose monitoring system with a portable blood glucose meter to determine insulin dose in cats with diabetes mellitus. J Vet Intern Med. 2011 Sep;25(5):1084-8. Epub 2011 Aug 30. PMID: 21985140.
  10. Osto, M., E. Zini, M. Franchini, C. Wolfrum, F. Guscetti, M. Hafner, M. Ackermann, CE Reusch, TA Lutz. Subacute endotoxemia induces adipose inflammation and changes in lipid and lipoprotein metabolism in cats. Endocrinology. 2011 Mar;152(3):804-15. Epub 2011 Jan 25. PubMed PMID: 21266508.
  11. Zini, E., M. Hafner, M. Osto, M. Franchini, M. Ackermann, TA Lutz, CE Reusch. Predictors of clinical remission in cats with diabetes mellitus. J Vet Intern Med. 2010 Nov-Dec;24(6):1314-21. Epub 2010 Sep 14. PubMed PMID: 20840299.
  12. Sieber-Ruckstuhl, N.S., E. Zini, M. Osto, M. Franchini, F.S. Boretti, M.L. Meli, B. Sigrist, TA Lutz, CE Reusch. Effect of hyperlipidemia on 11beta-hydroxysteroid-dehydrogenase, glucocorticoid receptor, and leptin expression in insulin-sensitive tissues of cats. Domest Anim Endocrinol. 2010 Nov;39(4):222-30. Epub 2010 Jul 14. PubMed PMID: 20688460.
  13. Franchini, M., E. Zini, M. Osto, K. Jablonski, K. Kaufmann, TA Lutz, CE Reusch, M. Ackermann. Feline pancreatic islet-like clusters and insulin producing cells express functional Toll-like receptors (TLRs). Vet Immunol Immunopathol. 2010 Nov; 15;138(1-2):70-8. Epub 2010 Aug 1. PubMed PMID: 20674989.
  14. Zini, E., M. Osto, D. Konrad, M. Franchini, N.S. Sieber-Ruckstuhl, K. Kaufmann, F. Guscetti, M. Ackermann, TA Lutz, CE Reusch. 10-day hyperlipidemic clamp in cats: effects on insulin sensitivity, inflammation, and glucose metabolism-related genes. Horm Metab Res. 2010 May;42(5):340-7. Epub 2010 Feb 16. PubMed PMID: 20162504.
  15. Zini E, M. Osto, S. Moretti, M. Franchini, P.H. Kook, H. Lutz, F. Guscetti, A. Perren, L.E. Hoelzle, M. Ackermann, TA Lutz, CE Reusch. Hyperglycaemia but not hyperlipidaemia decreases serum amylase and increases neutrophils in the exocrine pancreas of cats. Res Vet Sci. 2010 Aug;89(1):20-6. Epub 2010 Feb 4. PubMed PMID: 20132955.
  16. Moretti, S., F. Tschuor, M. Osto, M. Franchini, B. Wichert, M. Ackermann, T TA Lutz, CE Reusch, E. Zini. Evaluation of a novel real-time continuous glucose-monitoring system for use in cats. J Vet Intern Med. 2010 Jan-Feb;24(1):120-6. PubMed PMID: 20002556.
  17. Zini, E., M. Franchini, F. Guscetti, M. Osto, K. Kaufmann, M. Ackermann, TA Lutz, CE Reusch. Assessment of six different collagenase-based methods to isolate feline pancreatic islets. Res Vet Sci. 2009 Dec;87(3):367-72. Epub 2009 Apr 21. PubMed PMID: 19386336.
  18. Zini, E., M. Franchini, M. Osto, A. Vögtlin, F. Guscetti, P. Linscheid, K. Kaufmann, B. Sigrist, M. Ackermann, TA Lutz, CE Reusch. Quantitative real-time PCR detection of insulin signalling-related genes in pancreatic islets isolated from healthy cats. Vet J. 2010 Mar;183(3):287-93. Epub 2008 Dec 31. PubMed PMID: 19119030.
  19. Zini, E., M. Osto, M. Franchini, F. Guscetti, M.Y. Donath, A. Perren, R.S. Heller, P. Linscheid, M. Bouwman, M. Ackermann, TA Lutz, CE Reusch. Hyperglycaemia but not hyperlipidaemia causes beta cell dysfunction and beta cell loss in the domestic cat. Diabetologia. 2009 Feb;52(2):336-46. Epub 2008 Nov 26. PubMed PMID: 19034421.
  20. Fulurija, A., TA Lutz, K. Sladko, M. Osto, PY Wielinga, MF Bachmann, P. Saudan. Vaccination against GIP for the treatment of obesity. PLoS One. 2008 Sep 9;3(9):e3163. PubMed PMID: 18779862; PubMed Central PMCID: PMC2525840.
  21. Osto, M., PY Wielinga, B. Alder, N. Walser, TA Lutz. Modulation of the satiating effect of amylin by central ghrelin, leptin and insulin. Physiol Behav. 2007 Aug 15;91(5):566-72. Epub 2007 Mar 30. PubMed PMID: 17481674.